Functional Recovery after Experimental Stroke in Rats.

nathan whitmore and his rats

Link – PPAR-γ Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats. Abstract Background: Neoangiogenesis after cerebral ischemia in mammals is insufficient to restore neurological function, illustrating the need to design better strategies for improving outcomes. Our previous study has suggested that transcutaneous auricular vagus nerve stimulation (ta-VNS) induced angiogenesis and improved […]

Therapeutic effects of vagus nerve stimulation

Link – Therapeutic effects of children with refractory epilepsy after vagus nerve stimulation in Taiwan. Abstract BACKGROUND: Vagus nerve stimulation (VNS) is used as an add-on treatment for epilepsy. This study aimed to use Taiwanese nationwide registry data to analyze the therapeutic effects of VNS in children with refractory epilepsy (RE) and try to explore […]

Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury

Link – Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury by Regulating the NF-κB/NLRP3 Signaling Pathway. Abstract BACKGROUND: Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Oxidative stress, inflammation, and apoptosis are vital pathophysiological features post-TBI. OBJECTIVES: Research has shown that vagus nerve stimulation (VNS) can attenuate oxidative stress in […]

Vagus Nerve Stimulation in Patients with Covid-19?

Corona Virus

Link – Targeting the cholinergic anti-inflammatory pathway with vagus nerve stimulation in patients with Covid-19? Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), at the origin of the worldwide COVID-19 pandemic, is characterized by a dramatic cytokine storm in some critical patients with COVID-19. This storm is due to the release of high levels of […]

Epilepsy duration as predictor of response to vagus nerve stimulation.

Link – Epilepsy duration as an independent predictor of response to vagus nerve stimulation. Abstract BACKGROUND: Vagus nerve stimulation (VNS) is a form of neuromodulation that has been used to treat individuals with drug-resistant epilepsy (DRE). Although many retrospective studies have explored the predictors of VNS treatment efficacy, the data have been inconsistent, and no […]

Vagus nerve stimulation for treatment-resistant depression

Link – Vagus nerve stimulation for treatment-resistant depression: is this therapy distinct from other antidepressant treatments? Abstract BACKGROUND: The treatment-resistant depression (TRD) is a very disabling disease. OBJECTIVE: The aim of this article is to provide an overview of the therapeutic activity of vagus nerve stimulation (VNS) therapy system in TRD. We summarised the progress […]

Vagus nerve stimulation boosts the drive to work for rewards.

Link – Vagus nerve stimulation boosts the drive to work for rewards. Abstract Interoceptive feedback transmitted via the vagus nerve plays a vital role in motivation by tuning actions according to physiological needs. Whereas vagus nerve stimulation (VNS) reinforces actions in animals, motivational effects elicited by VNS in humans are still largely elusive. Here, we […]

Effects of vagus nerve stimulation for Parkinson’s disease.

Link – Differential effects of vagus nerve stimulation paradigms guide clinical development for Parkinson’s disease. Abstract BACKGROUND: Vagus nerve stimulation (VNS) modifies brain rhythms in the locus coeruleus (LC) via the solitary nucleus. Degeneration of the LC in Parkinson’s disease (PD) is an early catalyst of the spreading neurodegenerative process, suggesting that stimulating LC output […]

Effect of tVNS on Brain Processing of Food Cues

Link – Effect of Short-Term Transcutaneous Vagus Nerve Stimulation (tVNS) on Brain Processing of Food Cues: An Electrophysiological Study. Abstract Background: The vagus nerve plays an important role in the regulation of food intake. Modulating vagal activity via electrical stimulation (VNS) in patients and animal studies caused changes in food intake, energy metabolism, and body […]

Noninvasive Vagus Nerve Stimulation for Effective Acute Migraine Control?

Link – Is Noninvasive Vagus Nerve Stimulation a Safe and Effective Alternative to Medication for Acute Migraine Control? Abstract BACKGROUND: Noninvasive neuromodulation devices have been used for a variety of headache disorders, including cluster and migraine, since recently being cleared by the Federal Drug Administration. Although these devices have been touted as low-risk options for […]