Locations for brain stimulation in depressive disorders

Link – Locations for noninvasive brain stimulation in treating depressive disorders: A combination of meta-analysis and resting-state functional connectivity analysis. Abstract OBJECTIVE: Many noninvasive brain stimulation techniques have been applied to treat depressive disorders. However, the target brain region in most noninvasive brain stimulation studies is the dorsolateral prefrontal cortex. Exploring new stimulation locations may […]

tDCS on sleep quality and depression

Link – The effects of repeated transcranial direct current stimulation on sleep quality and depression symptoms in patients with major depression and insomnia. Abstract IMPORTANCE: Although several strategies using transcranial direct current stimulation (tDCS) have been investigated to treat major depressive disorder (MDD), the efficacy of this treatment for patients with MDD who also have […]

Altered directed functional connectivity of the right amygdala in depression

Link – Altered directed functional connectivity of the right amygdala in depression: high-density EEG study. Abstract The cortico-striatal-pallidal-thalamic and limbic circuits are suggested to play a crucial role in the pathophysiology of depression. Stimulation of deep brain targets might improve symptoms in treatment-resistant depression. However, a better understanding of connectivity properties of deep brain structures […]

Adjunctive Vagus Stimulation for Treatment-Resistant Depression

Link – Adjunctive Vagus Nerve Stimulation for Treatment-Resistant Depression: a Quantitative Analysis. Abstract Vagus nerve stimulation (VNS) has been increasingly studied in treating treatment-resistant depression (TRD), but the findings have been mixed. This updated meta-analysis was conducted to examine the efficacy and safety of adjunctive VNS for TRD. Controlled studies reporting on the efficacy and […]

tDCS in Depression Modulates Cortical Excitability

Link – Transcranial Direct Current Stimulation Over the Prefrontal Cortex in Depression Modulates Cortical Excitability in Emotion Regulation Regions as Measured by Concurrent Functional Magnetic Resonance Imaging: An Exploratory Study. Abstract BACKGROUND: A well-established impaired top-down network for effortful emotion regulation (ER) in major depressive disorder (MDD) includes the dorsal and ventromedial prefrontal cortex (PFC) […]

Depression and γ-tACS.

Link – LTD-like plasticity of the human primary motor cortex can be reversed by γ-tACS. Brain Stimul. 2019 Nov – Dec;12(6):1490-1499 Authors: Guerra A, Suppa A, Asci F, De Marco G, D’Onofrio V, Bologna M, Di Lazzaro V, Berardelli A Abstract BACKGROUND: Cortical oscillatory activities play a role in regulating several brain functions in humans. […]

New neuromodulation techniques for treatment resistant depression.

Link – New neuromodulation techniques for treatment resistant depression. Int J Psychiatry Clin Pract. 2020 Feb 18;:1-10 Authors: Andrei V, Mihaela BV Abstract In the treatment of depression, when pharmacotherapy, psychotherapy and the oldest brain stimulation techniques are deadlocked, the emergence of new therapies is a necessary development. The field of neuromodulation is very broad […]

Classifying Major Depressive Disorder using fNIRS

Link – Classifying Major Depressive Disorder using fNIRS during Motor Rehabilitation. IEEE Trans Neural Syst Rehabil Eng. 2020 Feb 07;: Authors: Zhu Y, Jayagopal JK, Mehta RK, Erraguntla M, Nuamah J, McDonald AD, Taylor H, Chang SH Abstract Major depressive disorder (MDD) has shown to negatively impact physical recovery in a variety of medical events […]

Effect of tVNS in depression.

Link – Neural networks and the anti-inflammatory effect of transcutaneous auricular vagus nerve stimulation in depression. J Neuroinflammation. 2020 Feb 12;17(1):54 Authors: Liu CH, Yang MH, Zhang GZ, Wang XX, Li B, Li M, Woelfer M, Walter M, Wang L Abstract Transcutaneous auricular vagus nerve stimulation (taVNS) is a relatively non-invasive alternative treatment for patients […]

VNS therapy in patients with depression

Link – Vagus nerve stimulation (VNS) therapy in patients with treatment resistant depression: A systematic review and meta-analysis. Compr Psychiatry. 2019 Dec 12;98:152156 Authors: Bottomley JM, LeReun C, Diamantopoulos A, Mitchell S, Gaynes BN Abstract BACKGROUND: Vagus nerve stimulation (VNS) therapy is approved for treatment-resistant depression (TRD). A recent 5-year comparative study prompted this review […]