Optimization of montages and electric currents in tDCS.

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Optimization of montages and electric currents in tDCS.

Abstract
In order to optimize the capability of transcranial Direct Current Stimulation (tDCS), electrode arrangements and the inward current stimulation are taken into account as two crucial factors. In this contribution, in order to specify the electrode positions, a detailed protocol is investigated, in which regarding the intended targeted regions, the optimal montages with an arbitrary number of electrodes are developed. After designing the positions of all active and returned electrodes, the corresponding inward current density is determined for each electrode. The outcomes of the simulation and the electric field distributions in the hand cortex prove that the proposed protocol is capable of improving the tDCS efficiency substantially in all head layers. Furthermore, in order to compare our approach with the other works found in the literature, a performance evaluation is curried out by calculating the maximum electric field distribution in the targeted region. This study shows that it improves tDCS efficiency virtually 2.5 times in comparison to High Definition (HD) montages in the gray matter and nearly 1.5 times in comparison to the other inner layers. Such an outstanding achievement in the gray matter can be regarded as an interesting standpoint in tDCS-rehabilitation studies.

PMID: 33039799 [PubMed – as supplied by publisher]

Comput Biol Med. 2020 Sep 26;125:103998

Authors: Khorrampanah M, Seyedarabi H, Daneshvar S, Farhoudi M

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